Cetylpyridinium chloride
Cetylpyridinium chloride is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Brand Name | Status | Last Update |
|---|---|---|
| 2080 dentistry night fresh | OTC monograph final | 2017-02-03 |
| 2080 dentistry night repair | OTC monograph final | 2017-02-03 |
| actisep | OTC monograph not final | 2018-12-11 |
| advanced guard | OTC monograph not final | 2022-06-28 |
| alcohol free antiseptic | OTC monograph not final | 2023-02-14 |
| antigingivitis/antiplaque | C200263 | 2023-11-13 |
| antiplaque solution | OTC monograph not final | 2023-05-23 |
| antiseptic | C200263 | 2023-12-04 |
| antiseptic oral rinse | OTC monograph not final | 2022-02-22 |
| antispetic | OTC monograph not final | 2022-06-29 |
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Clinical
Clinical Trials
52 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | 1 | 4 | — | 1 | 6 | 11 |
| Gingivitis | D005891 | HP_0000230 | K05.10 | 1 | 1 | 2 | 6 | 1 | 10 |
| Dental plaque | D003773 | — | — | 1 | 2 | 1 | 3 | — | 6 |
| Periodontal diseases | D010510 | — | K05.6 | — | 1 | 1 | 2 | 2 | 5 |
| Peri-implantitis | D057873 | EFO_1001390 | — | — | — | — | 1 | 2 | 3 |
| Coronavirus | D017934 | — | — | — | — | — | 1 | 1 | 2 |
| Sars-cov-2 | D000086402 | — | — | — | 1 | — | 1 | — | 2 |
| Viral load | D019562 | — | — | — | — | — | 1 | — | 1 |
| Polymerase chain reaction | D016133 | OBI_0000415 | — | — | — | — | 1 | — | 1 |
| Dentures | D003778 | — | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | 1 | — | 1 | 3 |
| Pharyngitis | D010612 | — | R07.0 | — | — | 1 | — | — | 1 |
| Chronic periodontitis | D055113 | EFO_0006343 | K05.3 | — | — | 1 | — | — | 1 |
| Herpes labialis | D006560 | EFO_1001347 | B00.1 | — | — | 1 | — | — | 1 |
| Hygiene | D006920 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | 3 | — | — | 1 | 4 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | 1 | — | — | 1 | 2 |
| Premature birth | D047928 | EFO_0003917 | O60 | — | 1 | — | — | — | 1 |
| Virus diseases | D014777 | — | B34 | — | 1 | — | — | — | 1 |
| Pharyngeal diseases | D010608 | — | — | — | 1 | — | — | — | 1 |
| Respiratory tract infections | D012141 | — | J06.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | 2 | — | — | — | — | 2 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | — | — | — | 2 | 2 |
| Oral hygiene | D009910 | — | — | — | — | — | — | 2 | 2 |
| Oral ulcer | D019226 | HP_0000155 | — | — | — | — | — | 1 | 1 |
| Halitosis | D006209 | — | R19.6 | — | — | — | — | 1 | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
| Virome | D000083422 | — | — | — | — | — | — | 1 | 1 |
| Depression | D003863 | — | F33.9 | — | — | — | — | 1 | 1 |
| Incidence | D015994 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cetylpyridinium chloride |
| INN | cetylpyridinium chloride |
| Description | Cetylpyridinium chloride is a pyridinium salt that has N-hexadecylpyridinium as the cation and chloride as the anion. It has antiseptic properties and is used in solutions or lozenges for the treatment of minor infections of the mouth and throat. It has a role as an antiseptic drug and a surfactant. It is a chloride salt and an organic chloride salt. It contains a cetylpyridinium. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCCCCCCCCCC[n+]1ccccc1.[Cl-] |
Identifiers
| PDB | — |
| CAS-ID | 123-03-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL34833 |
| ChEBI ID | 32915 |
| PubChem CID | 31239 |
| DrugBank | — |
| UNII ID | 6BR7T22E2S (ChemIDplus, GSRS) |
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Safety
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220 adverse events reported
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